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In a latest research, we claimed the identification and the characterization of a brand new atypical opioid receptor with one of a kind negative regulatory properties in the direction of opioid peptides.1 Our success showed that ACKR3/CXCR7, hitherto generally known as an atypical scavenger receptor for chemokines CXCL12 and CXCL11, is usually a wi
Gene expression Examination exposed that ACKR3 is very expressed in a number of brain locations equivalent to critical opioid action centers. Additionally, its expression levels are frequently increased than All those of classical opioid receptors, which additional supports the physiological relevance of its noticed in vitro opioid peptide scavengi